PI3K-AKT signalling pathway as a target for therapeutic intervention in Acute Lymphoblastic Leukemia.
Isolation, characterization and identification of anti cancer compounds from Indian medicinal plants.
Value addition of Curcumin and its testing as an anti leukemic therapy
Mapping normal and cancer cell signalling networks: towards single cell proteomics.
Teaching
Botany (Under Graduate Gurudas College)- since 2001
Founder Head: Department of Microbiology, Gurudas College (2002-2004)
Former Guest Faculty (Post Graduate Dept. Of Biotechnology; Presidency University)
Former Guest Faculty (Post Graduate Dept. Of Genetics; University of Calcutta)
Guest Faculty (Post Graduate Department of Microbiology; Bidhannagar Govt. College)
Patents
Mandal C, Pal S, Chatterjee M. Process for preparation of a biomarker specific for O-acetylated sialic acid useful for diagnosing, monitoring treatment outcome, and predicting relapse of lymphoblastic leukemia. 2004; US Patent No: 6693177 (Granted: 17/2/2004)
Mandal C, Pal S, Chatterjee M, Bhattacharya DK. Process for the preparation of O-acetylated sialic acid specific immunoglobulin and method of quantification there of. 2000: European Patent no: 1083181 (filed on 01.19.2000 and Granted: 03/14/2001).
Mandal C, Pal S, Chatterjee M, Bhattacharya DK. A process for the preparation of a novel biomarker specific for O-acetylated sialic acid useful for the diagnosis, monitoring outcome of treatment and prediction of relapse and biomarker prepared thereby; Indian Patent n: IN191209 [ Priority No: 1999DE000001192 filed on 8. 9.1999and Granted: 04/10/2003]
Important Publications
Priya K Gopal. Mausumi Paul and Santanu Paul. Curcumin induces caspase mediated apoptosis in JURKAT cells by disrupting the redox balance. Asian Pacific Journal of Cancer Prevention. 2014 :15(1):93-100.
Priya K Gopal, Mausumi Paul and Santanu Paul. Anti leukemic potential of different Fenugreek seed germplasms. Am Jr Soc Issu Humn. 2014: 45-49.
Tathagata Deb. Priya K Gopal, Durba Ganguly, Piyal Das, Manju Bikash Saha, Santanu Paul and Saurabh Das. Enhancement of anti-leukemic potential of 2-hydroxyphenyl azo-2-napthanol (HPAN) on MOLT-4 cells through conjugation with Cu(II). Royal Society of Chemistry Advances. 2014. (Accepted).
Damle RN, Temburni S, Banapour T, Paul S, Mongini PK, Allen SL, Kolitz JE, Rai KR, Chiorazzi N. T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients. Blood. 2012:120(12): 2438-2449.
Acharya S. N., Acharya, K., Paul, S. and Basu S. K. Antioxidant and antileukemic properties of selected fenugreek (Trigonella foenum-graecum L.) genotypes grown in Western Canada. Canadian Journal of Plant Science. 2011: 91: 99-105
Book Chapters
Gopal P and Paul S. Sustainable environmental technologies of the 21st Century. 2011:20-22. Green Technology and Environment: Efforts For Building A Sustainable Planet. The Science Association of Bengal, 2011.
Acharya, S. N., Basu, S. K. Acharya, K, Paul, S., Datta Banik, S. and Prasad, R. 2011. Fenugreek: A spice, forage and nutraceutical crop. In: De. A. K. (edited) Spices: The elixir of life. Chapter 7. pp. 115-136.
Paul S, McCarthy B and Paul M. Medicinal application of green tea and its polyphenolic catechins. Advances in medicinal plant research. Chapter 11, 2007:237-256 (Research Sign Post Publishing Company; New Delhi)
Paul M and Paul S. Bioplastics from microbes: A new approach towards sustainable environment. Man and Environment. Chapter 14, 2007:229-236 (APH Publishing Corporations; New Delhi).