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Studies on the formation of inclusion complexes of drugs with β-cyclodextrin (CD)
M CHOWDHURY, R BASU
Published in -
1996
Volume: 35
   
Issue: 10
Pages: 901 - 902
Abstract
Spectrophotometric studies of inclusion complex formation of β-CD with donors like phenothiazine drugs and acridine dyes and with acceptors like chloranil and trinitrobenzene have been studied in aqueous medium. In each case a 1:1 complex formation is observed, the formation constants of which are determined using Benesi-Hildebrand equation. Effect of β-CD on the charge transfer complexes between these two groups is found to be complicated because of larger size of the complexes compared to the β-CD cavity (6-6.5Å).
About the journal
JournalIndian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry
Publisher-
ISSN0376-4710