We consider a two-treatment two-period crossover design in the presence of possible carryover effects, where the treatment responses are binary. We provide some simple probability models incorporating the possible carryover effects. Asymptotic distributions of the estimates of the parameters under the proposed models are derived. We carry out tests for treatment difference and carryover effects. Finally we use a data set to illustrate the applicability of the proposed procedures. © 2010 The Korean Statistical Society.