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Single-substrate enzyme kinetics: The quasi-steady-state approximation and beyond
S DHATT, K BHATTACHARYYA
Published in SPRINGER
2013
Volume: 51
   
Issue: 5
Pages: 1467 - 1477
Abstract
We analyze the standard model of enzyme-catalyzed reactions at various substrate-enzyme ratios by adopting a different scaling scheme and computational procedure. The regions of validity of the quasi-steady-state approximation are noted. Certain prevalent conditions are checked and compared against the actual findings. Efficacies of a few other measures, obtained from the present work, are highlighted. Some recent observations are rationalized, particularly at moderate and high enzyme concentrations. © 2013 Springer Science+Business Media New York.
About the journal
JournalData powered by TypesetJournal of Mathematical Chemistry
PublisherData powered by TypesetSPRINGER
ISSN0259-9791
Open AccessYes