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Sequential nonparametric tests based on randomized play-the-winner rule for restricted bivariate alternatives
U BANDYOPADHYAY, A BISWAS
Published in Elsevier
1999
Volume: 79
   
Issue: 1
Pages: 45 - 57
Abstract
For comparing two treatment effects in a clinical trial under a univariate set-up, a sampling design called randomized play-the-winner (RPW) rule was used by different authors (see, e.g., ; ). The objective of using such a rule was to allocate more patients to the better treatment. The present work suggests a bivariate version of the RPW rule. The rule is used to propose some sequential-type nonparametric tests for the equivalence of two bivariate treatment effects against a class of restricted alternatives. Some exact and asymptotic results associated with the tests are studied and examined. The limiting proportions of allocations to the two treatments are also obtained.
About the journal
JournalData powered by TypesetJournal of Statistical Planning and Inference
PublisherData powered by TypesetElsevier
ISSN0378-3758