Header menu link for other important links
X
Selective synthesis of 6'-arylidene-1-aryl-3-aryl-spiro[pyrrolizidine-2,2'-cyclohexanone] by cycloaddition of azomethine ylides to dibenzylidene cyclohexanone
B GAYEN, A BANERJI
Published in HeteroCorporation
2015
Volume: 52
   
Issue: 3
Pages: 919 - 925
Abstract
Azomethine ylides derived in situ from l-proline and aryl aldehydes underwent regioselective and stereoselective cycloadditions with diaryl cycloahexanone to form a series of spiro-pyrrolizidine compounds. By using equimolar proportions of the reactants in DMF, only a single mono-adduct, namely 6'-arylidene-1-aryl-3-aryl-spiro[pyrrolizidine-2,2'-cyclohexanone], was formed, the second double bond in the dipolarophile remaining unaffected. Structure elucidation was achieved by detailed spectroscopic analyses and XRD studies. Interesting solid-state structural characteristics were revealed by XRD analysis. © 2014 HeteroCorporation.
About the journal
JournalJournal of Heterocyclic Chemistry
PublisherHeteroCorporation
ISSN0022-152X