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Relationship between fatty acid synthesis, transport and total lipid content during human fetal lung development
G SA, G SA, T DAS, T DAS, M MUKHERJEA, M MUKHERJEA
Published in -
1990
Volume: 27
   
Issue: 1
Pages: 43 - 47
Abstract
Levels of fatty acid binding proteins (FABPs), lipids as well as activities of fatty acid synthesizing enzymes such as fatty acid synthase and ATP-citrate lyase increase with gestation showing maximum at term in human fetal lung. However, the activity of ATP-citrate lyase showed the same trend up to 30 weeks of gestation before declining slightly at term. These results indicate the importance of supply and/or synthesis of fatty acids when lung surfactant synthesis begins, thereby showing a correlation between the FABPs, lipid pattern and the activities of fatty acid synthesizing enzymes during prenatal lung development.
About the journal
JournalIndian Journal of Biochemistry and Biophysics
Publisher-
ISSN0301-1208