A new 'turn-ON' fluorescent probe, pyrene appended thymine acetamide (PTA), with high sensitivity and selectivity for the detection of uric acid (UA) was developed and first time imaging of uric acid in living cells in water was achieved. 1H NMR and density functional studies on the system have been carried out to determine the nature of the interaction between probe PTA and UA. © The Royal Society of Chemistry 2016.

SUKHENDU MANDAL

Microbiology

P SAHOO

H S SARKAR

S DAS

K MAITI

M R UDDIN

University of Calcutta (informally known as Calcutta University or CU) is a collegiate public state university located in Kolkata, West Bengal, India.&nbsp;Within India it is recognized as a &quot;Five-Star University&quot; and accredited &quot;A&quot; Grade by National Assessment and Accreditation Council.

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The University of Calcutta has secured the Fifth position among the Universities of India in the prestigious &quot;Indian University Ranking 2019&quot; list, released by the NIRF of the Ministry of Human Resource Development, Government of India.

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It was established on 24 January 1857, and was one of the first institutions in Asia to be established as a multidisciplinary and Western-style university. Its alumni and faculty include several heads of state, heads of government, social reformers, prominent artists, only academy award winner and Dirac medal winner in India, many Fellows of the Royal Society and five Nobel laureates as of 2019 which is highest in South Asia.

University Of Calcutta

RSC Advances

A pyrrole-based rhodamine conjugate (CS-1) has been developed and characterized for the selective detection and quantification of 2′-deoxy-5-(hydroxymethyl)cytidine (5hmC) in human cancer cells with a simple chemosensing method. © The Royal Society of Chemistry.

Fulltext

2â€²-Deoxy-5-(hydroxymethyl)cytidine: estimation in human cancer cells with a simple chemosensor

A simple, sensitive, and rapid assay has been developed for detection of N-acyl homoserine lactone (HSL) autoinducers involved in bacterial quorum sensing (QS) by a new coumarin appended rhodamine derivative (RNC) ensembled with Cu2+. RNC-Cu2+ conjugate shows “turn on” fluorescence while binding with HSLs. The interaction of ensemble with HSL is found to be 1:1 stoichiometry on the basis of absorption and fluorescence titrations with the detection limit of 2.4 μM at neutral pH. NMR, IR titrations and DFT calculations were performed in order to demonstrate the sensing mechanism and the electronic properties of the receptor-donor complex. The present chemosensor improves upon any previous biosensor-based approaches to selectively quantitate HSL, both in cell-free and in whole-cell assay system. © 2017 Elsevier B.V.

Sensors and Actuators, B: Chemical

A chemosensor to recognize N-acyl homoserine lactone in bacterial biofilm

A simple new chemosensor, pyrene-appended 5-hydroxyisophthalic acid derivative (PIA), was developed and characterized for selective detection and quantification of cytosine in different human cancer cells. PIA shows "turn-on" fluorescence in presence of cytosine through intermolecular hydrogen bonding with a detection limit of 32 nM at neutral pH. © 2017 The Royal Society of Chemistry.

turn-on fluorescence sensing of cytosine: Development of a chemosensor for quantification of cytosine in human cancer cells

Bioorganic & Medicinal Chemistry Letters

Molecular recognition of pyrimidine nucleobases by triplex DNA receptors

WIREs Computational Molecular Science

The ORCA program system

Analytical Biochemistry

An amperometric uric acid biosensor based on multiwalled carbon nanotube–gold nanoparticle composite

Colloids and Surfaces B: Biointerfaces

Determination of isoproterenol and uric acid by voltammetric method using carbon nanotubes paste electrode and p-chloranil

Chemical Communications

Enzyme-free colorimetric assay of serum uric acid

Pyrene appended thymine derivative for selective turn-on fluorescence sensing of uric acid in live cells

Journal	Data powered by TypesetRSC Advances
Publisher	Data powered by TypesetRoyal Society of Chemistry
ISSN	2046-2069
Open Access	No