M K PODDAR

K C BHATTACHARYYA

J J GHOSH

University of Calcutta (informally known as Calcutta University or CU) is a collegiate public state university located in Kolkata, West Bengal, India.&nbsp;Within India it is recognized as a &quot;Five-Star University&quot; and accredited &quot;A&quot; Grade by National Assessment and Accreditation Council.

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The University of Calcutta has secured the Fifth position among the Universities of India in the prestigious &quot;Indian University Ranking 2019&quot; list, released by the NIRF of the Ministry of Human Resource Development, Government of India.

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It was established on 24 January 1857, and was one of the first institutions in Asia to be established as a multidisciplinary and Western-style university. Its alumni and faculty include several heads of state, heads of government, social reformers, prominent artists, only academy award winner and Dirac medal winner in India, many Fellows of the Royal Society and five Nobel laureates as of 2019 which is highest in South Asia.

University Of Calcutta

Potentiating effect of cannabidiol on delta9-tetrahydrocannabinol-induced changes in hepatic enzymes.

Biochemical Pharmacology

There is no shift of emission maximum (F470nm) of bovine serum albumin (BSA)-l-anilino-8-naphthatene sulphonic acid (ANS) complex in the pesence of delta-9-tetrahydrocannabinol (delta-9-THC) alone and cannabidiol (CBD) or cannabinol (CBN) in the presence and absence of delta-9-THC. Delta-9-THC (1.66-13.33 μM) and CBD at higher concentrations (13.33-20.0 μM) produce a concentration-dependent significant quenching of fluorescence of BSA-ANS complex, but CBN (l.66-20.0 μM) as well as CBD at lower concentrations (1.66-6.66 μM) fails to produce any significant change in Iluorescence intensity under similar conditions. Furthermore, neither CBD nor CBN is able to affect the delta-9-THC-induced quenching of fluorescence intensity of BSA-ANS complex. These results indicate that the binding of cannabinoids to the ANS binding sites of BSA molecule are in the order detta-9-THC &gt; CBr3 &gt; CBN, and CBD or CBN does not have any influence on the binding of delta-9-THC to BSA molecules under these conditions. © 1984 The Biochemical Society.

Bioscience Reports

Interactions of cannabinoids with bovine serum albumin

Potentiating effect of cannabidiol on Î”9-tetrahydrocannabinol-induced changes in hepatic enzymes

The effect of intraperitoneal administration of cannabis extract, Δ9-tetrahydrocannabinol (THC) and lysergic acid diethylamide (LSD), both at high (50 mg/kg, 100 mg/kg and 100 μg/kg respectively) and low (10 mg/kg, 10 mg/kg and 10 μg/kg respectively) doses, on the rat liver tyrosine α-ketoglutarate transaminase and tryptophan pyrrolase activity was studied and found that cannabis extract and Δ9-tetrahydrocannabinol, but not LSD, increased the above two enzyme activities after 6 hr of injection. © 1972.

Effect of cannabis extract, Î”9-tetrahydrocannabinol and lysergic acid diethylamide on rat liver enzymes

Journal of Pharmacy and Pharmacology

The content of (-)Δ9-trans-tetrahydrocannabinol (Δ9-THC) does not explain all biological activity of some Brazilian marihuana samples

British Journal of Pharmacology

A metabolic interactionin vivobetween cannabidiol and Δ1-tetrahydrocannabinol

Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism

Journal	Biochemical Pharmacology
Publisher	-
ISSN	0006-2952