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Peanut proteins in periodate specific anion sensing: An ensuing reduction in allergic response
S K GHATAK, S SEN, D MAJUMDAR, A SINGHA,
Published in Elsevier Ltd
2016
PMID: 26675870
Volume: 197
   
Pages: 1286 - 1291
Abstract
Peanut proteins conarachin II, conarachin I and arachin were found to behave as highly selective fluorescence sensors for periodate amongst a set of different anions. The interactions of the proteins with periodate were also confirmed by other spectral methods and enzyme linked immunosorbent assay (ELISA). The results indicate a selective interaction of peanut proteins with periodate amongst chloride, sulphate, iodide, phosphate, nitrate, nitrite, bromide, fluoride, persulphate, acetate, thiosulphate, arsenite, arsenate, sulphite, and iodide. Periodate sensing using different synthesized organic molecules are already reported in the literature. In this article we report the efficiency of peanut proteins as anion sensor which are bioactive and inexpensive too. The protein periodate interactions have also resulted in a simultaneous reduction in allergenicity of the peanut proteins. A change in the secondary structure of the protein was found responsible for this change which was further established with the help of circular dichroism and Raman spectroscopy. © 2015 Elsevier Ltd. All rights reserved.
About the journal
JournalData powered by TypesetFood Chemistry
PublisherData powered by TypesetElsevier Ltd
ISSN0308-8146