From Kopsia fruticosa a new alkaloid, termed kopsine, C 22 H 26 N 2 O 4 , m. p. 217-218° (dec.), has been obtained. The isolation and properties of this alkaloid have been studied. On hydrolysis, it yields a base, kopsidine, C 20 H 24 N 2 O 3 , m. p. 142° and on hydrogenation, a dihydro derivative, m. p. 218° (dec.). © 1949, American Chemical Society. All rights reserved.