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Neurotoxicity of lanthanum chloride in newborn chicks
A BASU
,
K CHAKRABARTY
,
G C CHATTERJEE
Published in ELSEVIER SCI IRELAND LTD
1982
DOI:
10.1016/0378-4274(82)90005-4
Volume: 14
Issue: 43467
Pages: 21 - 25
Abstract
Acute intraperitoneal administration of lanthanum chloride to newborn chicks at the single dose of 250 mg/kg body weight inhibits calcium binding to brain synaptosomal membrane. There is also marked depression in the activities of neural Ca2+-ATPase, Mg2+-ATPase, and cholinesterase after acute lanthanum chloride intoxication. The inhibition of these enzymes in relation to depletion of calcium binding to the synaptosomal membrane has been discussed. © 1982.
Topics:
Calcium
(55)%
55% related to the paper
and
Chloride
(50)%
50% related to the paper
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Journal
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Toxicology Letters
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ELSEVIER SCI IRELAND LTD
ISSN
0378-4274
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