Microwave irradiation of a solid mixture of aryl 1,2-diketones, l-proline, and ammonium acetate (excess) for 15 min produces 2,3-diaryl-6,7-dihydro-5H- pyrrolo[1,2-a]imidazoles in moderate yields. Mechanistically this one-pot three-component reaction generates pyrroloimidazoles through the intramolecular cyclization of 1,2-diimine intermediates derived from the condensation of aryl 1,2-diketones, l-proline, and ammonia in 1:1:1 molar proportion. The significant advantages of this methodology are cost-effectiveness, operational simplicity, and reduced reaction time. © 2013 Elsevier Ltd. All rights reserved.

ANIMESH PRAMANIK

Chemistry

S MAITY

S PATHAK

University of Calcutta (informally known as Calcutta University or CU) is a collegiate public state university located in Kolkata, West Bengal, India.&nbsp;Within India it is recognized as a &quot;Five-Star University&quot; and accredited &quot;A&quot; Grade by National Assessment and Accreditation Council.

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The University of Calcutta has secured the Fifth position among the Universities of India in the prestigious &quot;Indian University Ranking 2019&quot; list, released by the NIRF of the Ministry of Human Resource Development, Government of India.

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It was established on 24 January 1857, and was one of the first institutions in Asia to be established as a multidisciplinary and Western-style university. Its alumni and faculty include several heads of state, heads of government, social reformers, prominent artists, only academy award winner and Dirac medal winner in India, many Fellows of the Royal Society and five Nobel laureates as of 2019 which is highest in South Asia.

University Of Calcutta

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Microwave assisted synthesis of 2,3-diaryl-6,7-dihydro-5H-pyrrolo[1,2 a]imidazoles through direct condensation of aryl 1,2-diketones and l-proline under solvent-free condition

Journal	Tetrahedron Letters
Publisher	-
ISSN	0040-4039
Open Access	No