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Microwave Assisted Green Synthesis of Pyrazole, 1, 2, 3-Triazole Based Novel Benzohydrazones and Their Antibacterial Activities
K SRAVANTHI, P SNEHALATHA, N J P SUBHASHINI
Published in WILEY
2018
Volume: 55
   
Issue: 2
Pages: 508 - 516
Abstract
A series of novel pyrazole, triazole based benzohydrazones (7a-l) were synthesized via conventional and microwave methods in the presence of acetic acid catalyst. Microwave method provided green and economical approach towards the synthesis of novel Schiff bases (7a-l). Some intermediates and all the final compounds were characterized by NMR, mass, and elemental analysis. The compounds were screened for their in vitro antibacterial activity against Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive bacteria (Staphylococcus aureus and Bacillus cereus). Compounds 7e and 7g showed good antibacterial activity.
About the journal
JournalData powered by TypesetJournal of Heterocyclic Chemistry
PublisherData powered by TypesetWILEY
ISSN0022-152X