An efficient CuI catalyzed intramolecular Ullmann-type C−N coupling reaction is described here. Newly substituted 1H-benzo[4,5]imidazo[1,2-a]pyrrolo[3,4-c]pyridine-1,3,5(2H, 11H)-trione has been easily synthesized from ortho halogenated N-substituted pyrrolo[3,4-c]pyridine-1,3,6(5H)-triones in presence of CuI catalyst and K2CO3 base without any ligand. This procedure is based on intramolecular Ullmann-type reaction and provides a proficient method of making fused tetracyclic heterocycles. © 2019 Elsevier Ltd

CHHANDA MUKHOPADHYAY

Chemistry

P MAITY

University of Calcutta (informally known as Calcutta University or CU) is a collegiate public state university located in Kolkata, West Bengal, India.&nbsp;Within India it is recognized as a &quot;Five-Star University&quot; and accredited &quot;A&quot; Grade by National Assessment and Accreditation Council.

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The University of Calcutta has secured the Fifth position among the Universities of India in the prestigious &quot;Indian University Ranking 2019&quot; list, released by the NIRF of the Ministry of Human Resource Development, Government of India.

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It was established on 24 January 1857, and was one of the first institutions in Asia to be established as a multidisciplinary and Western-style university. Its alumni and faculty include several heads of state, heads of government, social reformers, prominent artists, only academy award winner and Dirac medal winner in India, many Fellows of the Royal Society and five Nobel laureates as of 2019 which is highest in South Asia.

University Of Calcutta

Tetrahedron

New 2H-pyrrolo[3,4-c]pyridine-1,3,6(5H)-trione-based fluorophores have been synthesized by a single-step procedure in an ambient reaction condition. By this protocol, a total of 44 new compounds were generated and the photophysical property of 23 compounds was studied in detail. These fluorophores show good fluorescence activity and illustrate high selectivity for Fe3+/Fe2+ cation in the 10-7 (M) range. Notably, this 2H-pyrrolo[3,4-c]pyridine-1,3,6(5H)-trione moiety is first used as a turn-off chemosensor for the Fe3+/Fe2+ cation. In addition, this probe was further applied for imaging Fe3+ in living HepG2 cells. © 2018 American Chemical Society.

Fulltext

ACS Omega

Pyrrolo[3,4- c]pyridine-Based Fluorescent Chemosensor for Fe3+/Fe2+ Sensitivity and Their Application in Living HepG2 Cells

A unique, convenient and efficient multicomponent one-pot synthetic approach to access a wide variety of pyrrolo[3, 4-c] pyridines has been developed. This is the first report of the direct synthesis of pyrrolo[3, 4-c]pyridine amido-triones from primary amines, malononitrile and dialkylacetylenedicarboxylate in an aqueous medium without using any catalyst. The newly synthesized compounds are fluorescent in nature and photophysical properties of some selective compounds have been carried out. In addition, a comparative photophysical study of some selective fluorophores was also performed in a wide variety of solvents. © 2018 Wiley-VCH Verlag GmbH &amp; Co. KGaA, Weinheim

ChemistrySelect

A Facile, Convenient and Catalyst-Free One-Pot Route to Fluorescent Pyrrolo[3, 4-c]pyridines via Multicomponent Strategy in Aqueous Medium

Catalysts

Bio-based Catalysts from Biomass Issued after Decontamination of Effluents Rich in Copper—an Innovative Approach towards Greener Copper-based Catalysis

ACS Sustainable Chemistry & Engineering

Graphene Oxide as Metal-Free Catalyst in Oxidative Dehydrogenative C–N Coupling Leading to α-Ketoamides: Importance of Dual Catalytic Activity

Chemical Engineering & Technology

Highlights: Chem. Eng. Technol. 8/2017

Intramolecular Ullmann-type Câˆ’N coupling for the synthesis of substituted benzo[4,5]imidazo[1,2-a]pyrrolo[3,4-c]pyridines

Journal	Data powered by TypesetTetrahedron
Publisher	Data powered by TypesetElsevier Ltd
ISSN	0040-4020
Open Access	No