Glucagon (0.1 mg · 100 g body wt-1) increased norepinephrine (NE) content in adult pigeon (31%) and parakeet (58%), decreased NE content in the adrenal medulla of newly-hatched pigeon (36%), parakeet (52%), and crow (44%) 0.5 h after treatment. Epinephrine (E) content decreased to 26% and 59% of control values, respectively, in newly-hatched pigeon and parakeet 0.5 h after treatment. Glucagon produced hyperglycemia irrespective of age and species. The results indicate that aging modulates glucagon-induced changes of catecholamine (CA) content. In the innervated (I) adrenal gland of pigeon, glucagon caused a 31% increase of NE content 0.5 h after injection, a 46% decrease of NE content 12 h after injection, and a 192% increase of NE 24 h after injection. In the I gland of pigeons, glucagon also caused a 61% decrease of E content 4 h after injection, and brought about a 100% increase of E 24 h after injection. Glucagon-induced changes of CA content differ significantly between the I and denervated (D) glands. The results indicate that the splanchnic nerve regulates release and/or resynthesis of CA induced by glucagon. © 1991 Springer-Verlag.

S K MAHATA

A GHOSH

University of Calcutta (informally known as Calcutta University or CU) is a collegiate public state university located in Kolkata, West Bengal, India.&nbsp;Within India it is recognized as a &quot;Five-Star University&quot; and accredited &quot;A&quot; Grade by National Assessment and Accreditation Council.

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The University of Calcutta has secured the Fifth position among the Universities of India in the prestigious &quot;Indian University Ranking 2019&quot; list, released by the NIRF of the Ministry of Human Resource Development, Government of India.

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It was established on 24 January 1857, and was one of the first institutions in Asia to be established as a multidisciplinary and Western-style university. Its alumni and faculty include several heads of state, heads of government, social reformers, prominent artists, only academy award winner and Dirac medal winner in India, many Fellows of the Royal Society and five Nobel laureates as of 2019 which is highest in South Asia.

University Of Calcutta

Influence of age and splanchnic nerve on glucagon-induced changes of adrenomedullary catecholamine content and blood glucose level in the avian group

Journal of Comparative Physiology B

Oxytocin (0.25 IU/100 g body wt) was injected intraperitoneally only once to unilaterally splanchnic denervated pigeons. The effects were investigated after 0.5, 4, 12, 24, 72, 144 and 216 h of administration. The findings revealed that oxytocin caused the release of more norepinephrine (NE) from the denervated glands up to 24 h after treatment. In contrast, oxytocin-induced release of epinephrine (E) showed no significant difference in between the innervated and the denervated glands after 0.5 h of treatment. Strikingly, oxytocin brought about release of more E from the denervated glands after 24 h of treatment. This indicates that the first phase of NE release and the second phase of E release are neurally regulated. The findings further revealed that the resynthesis of both NE and E was faster in the innervated glands after 216 h of oxytocin treatment. This clearly points out that the splanchnic nerve accelerates resynthesis of both NE and E induced by oxytocin. © 1991.

Regulatory Peptides

Neural influence on oxytocin-induced changes of adrenomedullary catecholamines in the pigeon

Insulin-induced ( 4 IU 100 g b. wt.) changes of adrenomedullary catecholamines (CA) were investigated in unilaterally splanchnic denervated pigeons 0.5, 4, 12, 24, 72, 144 and 216 h after injection. Insulin caused depletion of more norepinephrine (NE) from the denervated glands 0.5 h after treatment. This indicates that the splanchnic nerve prevents early phase of insulin-induced depletion of NE. Accelerated resynthesis of NE exceeding the control value was more in the innervated glands 24 h after administration. Insulin brought about augmented synthesis of epinephrine (E) surpassing the control value in the innervated glands 72 h after treatment. The findings point out that the splanchnic nerve stimulates resynthesis of NE and synthesis of E induced by insulin. © 1990.

Neuroscience Letters

Neural influence on the action of insulin in the adrenomedullary catecholamine content in the pigeon

Reserpine at three doses (0.05, 0.2, and 0.8 mg/100 g body wt) has been injected intraperitoneally to seven unilaterally splanchnic denervated avian species, in order to ascertain the neural regulation of its action in avian adrenal medulla. The adrenomedullary catecholamines (CA) were estimated at 24 hr after reserpine injection. The findings revealed that reserpine at high doses caused 66-92% depletion of total CA from both the innervated and the denervated glands in all the species investigated. The low dose of reserpine in the passerine (common myna and bulbul) birds resulted in 40-84% reduction of both norepinephrine (NE) and epinephrine (E) from the adrenal glands irrespective of its nerve supply. As a contrast, it depleted 60-80% of both NE and E from the innervated glands as compared to 17-43% reduction from the denervated glands in nonpasserine (woodpecker, parakeet, and koel) birds. Interestingly, in other nonpasserine (pigeon and duck) birds, the low dose of reserpine depleted 66-71% of NE from the innervated glands as compared to only 2-13% reduction from the denervated glands. But in these birds, 60-85% depletion of E, however, occurred independent of neural regulation. The findings suggest that at high doses depletion of CA by reserpine is controlled by some nonneurogenic mechanisms. Generally speaking, at a low dose of reserpine, the splanchmic nerve probably modulates depletion of CA from the adrenal medulla of the nonpasserine birds while the same is governed by some nonneurogenic mechanisms in the passerine birds. © 1989.

General and Comparative Endocrinology

Influence of splanchnic nerve on reserpine action in avian adrenal medulla

A single intraperitoneal (IP) melatonin injection (0.5 mg/100 g body wt.) caused an increase in norepinephrine (NE) fluorescence and elevation of NE content in newly-hatched pigeons (Columba livia), but a reduction of NE fluorescence and depletion of NE content in the adrenal medulla of newly-hatched crows (Corvus splendens) after 0.5 h of treatment. In contrast, in adults melatonin caused increase in NE fluorescence and elevation of NE content only in the parakeet (Psittacula krameri). Half an hour of IP melatonin treatment (0.5 mg/100 g body wt.) induced release of epinephrine (E) from the adrenal medulla of newly-hatched pigeon and parakeet. In contrast, in the adults melatonin caused more than a two-fold increase in E in the pigeon, and a significant increase in the crow. Single IP melatonin injection (0.5 mg/100 g body wt.) caused hypoglycemia in the newly-hatched parakeet and adult pigeon, and hyperglycemia in newly-hatched pigeon after 0.5 h of treatment. Melatonin failed to regulate glucose homoeostasis in newly-hatched and adult crow. Splanchnic denervation of the left adrenal gland was performed in the adult pigeon. The right adrenal served as the innervated gland. Melatonin-induced modulation of catecholamines following a single IP injection (0.5 mg/100 g body wt.) revealed significant increases in NE fluorescence and NE content at 4 and 12 h after treatment in the denervated gland only, which gradually approached normal levels 9 days after treatment. In contrast, E content showed more than a two-fold increase over the control value in both the innervated and denervated glands 0.5 and 24 h after treatment. At 9 days after treatment, E content showed significant depletion in the innervated gland. The results of this study indicate that melatonin modulates catechol hormone content in avian adrenal medulla, and also regulates glucose homoeostasis (except in the crow). The splanchnic nerve plays a vital role in the synthesis of NE but has no effect on E. © 1988 Springer-Verlag.

Influence of age and splanchnic nerve on the action of melatonin in the adrenomedullary catecholamine content and blood glucose level in the avian group

Catechol hormones (Norepinephrine and Epinephrine) content in the adrenal medulla of 25 species of the newly-hatched and adult birds were investigated. Norepinephrine (NE) and Epinephrine (E) were found to be the major hormones in the adrenal medulla of the newly-hatched passerine and non-passerine birds respectively. E was the preponderant hormone in the adrenal medulla of the adult passerine birds. The adrenal medulla of the adult non-passerine birds produced either NE as the predominant catechol hormone or NE and E in almost equal proportion as the adrenomedullary hormones. © 1986 Taylor & Francis Group, LLC.

Journal	Data powered by TypesetJournal of Comparative Physiology B
Publisher	Data powered by TypesetSpringer-Verlag
ISSN	0174-1578