Background: Nasobronchial allergic manifestations are highly prevalent in the Kolkata population, resulting in urticaria, allergic rhinitis, and extreme cases of bronchial asthma. Identification of etiologic factor(s) is of primary importance to provide patients with the best possible diagnosis and treatment. Unfortunately, baseline information in this respect from developing countries with poor economies is still fragmentary. Methods/Data base: Skin prick tests with 17 common aeroall ergens were done on 682 patients with a history of different nasobronchial allergic complaints to evaluate the frequency of immediate hypersensitivity reactions. The influence of age and gender, if any, on allergen sensitivity was also investigated. Results/Conclusion: The most common aeroallergens identified so far are house dust followed by cotton, kapok, pollen of Cocos nucifer and Brassica nigra, and two species of house dust mite - Dermatophagoides pteronyssinus and D. farinae. They account for about 74% of nasobronchial allergy in the Kolkata population. The frequency of positive skin reactions was found to be independent of age and gender. © 2006 Hogrefe & Huber Publishers.