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I-Motifs are more stable than G-quadruplexes in a hydrated ionic liquid
Hisae Tateishi-Karimata, Miki Nakano, , Shigenori Tanaka, Naoki Sugimoto
Published in
Volume: 51
Issue: 32
Pages: 6909 - 6912
Thermodynamic analyses and molecular dynamics calculations demonstrated that i-motifs in a hydrated ionic liquid of choline dihydrogen phosphate (choline dhp) were more stable than G-quadruplexes due to choline ion binding to loop regions in the i-motifs. Interestingly, the i-motifs formed even at physiological pH in the choline dhp-containing solution. This journal is
About the journal
JournalChemical Communications