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Free radical scavenging and nos activation properties of water soluble crude polysaccharide from Pleurotus ostreatus
P MITRA, S KHATUA,
Published in -
2013
Volume: 6
   
Issue: 3
Pages: 67 - 70
Abstract
The aim of this study was to investigate the antioxidant activity using different in vitro assays and nitric oxide synthase activation property of crude water soluble polysaccharide from P. ostreatus. The polysaccharide was isolated by hot water extraction and physico-chemical investigation revealed that it contained high amount of carbohydrate (mostly β-glucan) and low amount of protein and phenolic compounds. EC50 values for scavenging of hydroxyl radical and superoxide radical as well as chelating ability of ferrous ion were 665, 390 and 370 μg/ml respectively. The polysaccharide also showed potential nitric oxide synthase activation properties. This mushroom might be a good source of bioactive compounds.
About the journal
JournalAsian Journal of Pharmaceutical and Clinical Research
Publisher-
ISSN0974-2441
Open AccessNo