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Etiological factors for the persistence of endemic goiter in selected areas of Siddharthnagar district in Eastern Uttar Pradesh, India
Published in Freund Publishing House Ltd
Volume: 22
Issue: 4
Pages: 317 - 325

Aim: To assess the prevalence of goiter, state of iodine nutrition of the population, consumption pattern of common goitrogenic food, and distri-bution of iodine through edible salt in selected CD Blocks of Siddharthnagar district in Eastern Uttar Pradesh. Methods: Goiter survey among 1,862 school children, aged 6-12 years, of both sexes, and analysis of iodine (I) and thiocyanate (SCN) in 240 urine samples, and iodine content in 210 edible salt samples collected from the selected study areas. Results: The prevalence of goiter was 26.3% (grade 1: 23.2%; grade 2: 3.1%). Median urinary iodine level was 6.0 ug/dl, and 42% had concentration <5 fig/dl. Mean (SD) urinary SCN was 0.75 (0.4) mg/dl. Only 17.1% of salt samples had iodine level >15 ppm; 82.9% had <15 ppm. Conclusion: Consumption of inadequately iodized salt and cyanogenic plant foods containing goitrogenic/anti-thyroidal substances by the people of the studied region are possible reasons for the persistence of goiter during the post salt iodination phase. © Freund Publishing House Ltd., London.

About the journal
JournalJournal of Pediatric Endocrinology and Metabolism
PublisherFreund Publishing House Ltd
Open AccessNo