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Effect of heat-shock & nutritional stress on the expression of a neutral thiol protease in Leishmania donovani promastigotes
K GHOSHAL, G CHAUDHURI, A B BANERJEE
Published in -
1989
Volume: 89
   
Pages: 170 - 176
Abstract
The soluble intracellular protease was partially purified from L. donovani promastigotes. The activity of this enzyme increased with increase in temperature from 25 degrees C to 37 degrees C and was active optimally at 70 degrees C. This protease activity appeared to be decreased due to heat-shock of the promastigotes for 4 h at 37 degrees C and increased due to nutrient starvation. Inhibition of the protease by p-chloromercuribenzoate and iodoacetamide suggested that this enzyme could be a thiol protease.
About the journal
JournalIndian Journal of Medical Research - Section A Infectious Diseases
Publisher-
ISSN0019-5340