The design of Radio Frequency Identification RFID network , [3-5], , , ,  hence plays a significant role for successfully deploying large-scale applications , , , . This is especially true when the tagged object is on item-level. This paper discusses issues that should be considered in design of RFID network; analyzes the potential impacts of different RFID network design on the existing enterprise network  and presents the Distributed Design of Universal lightweight RFID system ,  for Large-Scale RFID operation for different RFID deployment environment [13-16] and computing platforms, which has the advantage of the rapid development of new scene-oriented RFID system. Customization and reconfiguration with lightweight , [4-6] capabilities are the aspirations of our developed RFID distributed system for large scale operation. Based on OSGi Open Service Gateway Initiative technology [17-19] and its Service-Oriented development mode, the paper describes the distributed service component framework and components design method for universal RFID system. © 2011 IEEE.