Header menu link for other important links
X
Changes in the nuclear envelope in laminopathies
S DUTTA, M BHATTACHARYYA, K SENGUPTA
Published in Springer New York LLC
2018
Volume: 1112
   
Pages: 31 - 38
Abstract
Double-membrane-bound nucleus is the major organelle of every metazoan cell, which controls various nuclear processes like chromatin maintenance, DNA replication, transcription and nucleoskeleton-cytoskeleton coupling. Nuclear homeostasis depends on the integrity of nuclear membrane and associated proteins. Lamins, underlying the inner nuclear membrane (INM), play a crucial role in maintaining nuclear homeostasis. In this review, we have focussed on the disruption of nuclear homeostasis due to lamin A/C mutation which produces a plethora of diseases, termed as laminopathies. © Springer Nature Singapore Pte Ltd. 2018.
About the journal
JournalData powered by TypesetAdvances in Experimental Medicine and Biology
PublisherData powered by TypesetSpringer New York LLC
ISSN0065-2598