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Antihepatotoxic activity of Chelidonium majus
S MITRA, M GOLE, K SAMAJDAR, R K SUR, B N CHAKRABORTY
Published in -
1992
Volume: 30
   
Issue: 2
Pages: 125 - 128
Abstract
The efficacy of an alcohol extract of Chelidonium majus as an antihepatotoxic agent was tested on rats with CCl4-induced hepatic injury. CCl4 (1 ml/kg; twice a week) and extract (125 mg/kg/day) were administered simultaneously. The parameters studied to assess liver damage were plasma ALAT, ASAT, AIP, LDH, bilirubin, cholesterol and liver histology. Significant protection toward CCl4-induced elevation of plasma enzymes, changes in bilirubin, cholesterol, and microscopic liver damage was observed. These results indicate the hepatoprotective action of the extract.
About the journal
JournalInternational Journal of Pharmacognosy
Publisher-
ISSN0925-1618