Header menu link for other important links
X
An Efficient Phosphotungstic Acid Catalysed Synthesis of 4,5-Dioxopyrrolidines and Study of the Mechanistic Effect of the Solvent on the Reaction
S BASU, T GHOSH, S MAITY, P GHOSH,
Published in Wiley-Blackwell
2019
Volume: 4
   
Issue: 19
Pages: 5763 - 5767
Abstract

An efficient protocol for the synthesis of dioxopyrrolidine scaffolds has been established using phosphotungstic acid as an effective catalyst in a multicomponent reaction of aromatic primary amines, dialkyl acetylene dicarboxylates and formaldehyde at room temperature in alcohol as a green solvent. In this methodology, the reactant solvent has an important part and is involved in the reaction mechanism to increase the versatility of the product. This protocol involves environment friendly, cost effective methodology with a comparatively simple reaction mechanism. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

About the journal
JournalData powered by TypesetChemistrySelect
PublisherData powered by TypesetWiley-Blackwell
ISSN2365-6549
Open AccessNo