Channel routing and crosstalk minimization are important issues while we talk about high-performance circuits for VLSI physical design automation. Interconnection among the net terminals satisfying constraints in an intelligent way is a necessity to realize a circuit in a minimum possible area, as this is a primary requirement to reduce cost as well as to increase yield. In this paper, along with area minimization, the performance of the computed circuits has also been enhanced by computing routing solutions with a specified amount of bottleneck crosstalk in two-layer channel routing. Usually, crosstalk is measured by the amount of overlapping of a pair of nets assigned to adjacent tracks. The crosstalk minimization problem in the reserved two-layer Manhattan channel routing model is NP-hard. Thus, in this paper, heuristic algorithms have been devised to optimize bottleneck crosstalk in order to augment circuit performance in two-layer channel routing. Experimental results obtained are highly encouraging. © 2020, Springer Nature Singapore Pte Ltd.