Header menu link for other important links
X
Activated alumina ball catalyzed expeditious synthesis of 2-alkylbenzimidazoles with special emphasis on susceptible side chains possessing amide functionality
Published in SCIENTIFIC PUBL-INDIA
2013
Volume: 90
   
Issue: 10
Pages: 1737 - 1748
Abstract
A solvent- and chromatography-free, non-hazardous green protocol for the synthesis of 2-alkylbenzimidazoles has been developed under neutral conditions with water as the only by-product. Activated alumina balls, which have been shown previously to assist in amidation reaction, also catalyze very successfully the condensation of benzene-1,2-diamines with carboxylic acids to produce the corresponding benzimidazoles. This methodology is also applicable to susceptible side chains possessing an amide functionality.
About the journal
JournalJournal of the Indian Chemical Society
PublisherSCIENTIFIC PUBL-INDIA
ISSN0019-4522
Open AccessNo