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Action of citreoviridin, a mycotoxin from Penicillium citreoviride on the gamma-aminobutyric acid metabolism of the central nervous system
S C DATTA, J J GHOSH
Published in -
1983
Volume: 21
   
Pages: 89 - 92
Abstract
Effect of treatment with different doses of citreoviridin, a mycotoxin from Penicillium citreoviride NRRL 2579, inhibited the brain GAD activity both under in vivo and in vitro conditions with concomitant reduction in GABA level. GABA-T activity is unaltered except in vitro in cerebral hemispheres where an increase is noted. It is suggested that citreoviridin neurotoxicity is related to the GABA metabolism of central nervous system. © 1983.
About the journal
JournalToxicon
Publisher-
ISSN0041-0101