Computer aided diagnostic is one of the most active research area and has huge impact on the health care industry. With the advent of intelligent methods, biomedical data processing becomes easier and less error prone. Moreover, remote health care is also possible using the IoT infrastructure. However, data security over the network is always considered as a challenge. Biomedical data are generally sensitive to external disturbances and small manipulation in the data may cause huge difference in the ultimate result. Wrong diagnosis can be life threatening in some scenarios or can be severe in almost every instance. Therefore, biomedical data security is one of the major challenge and necessary for remote health care. In this work, some application of cryptographic methods have been discussed which are used to protect biomedical images from unwanted modifications and access. This work can be highly beneficial in future research in the field of biomedical image protection as well as multimedia data security. © 2019 IEEE.