A simple one-pot procedure for the conversion of 2-hydroxy-2-(2′- hydroxy-aryl)-1,3-indanediones to 4-substituted benzoxazinones has been developed. The process constitutes an interesting acid-catalyzed rearrangement followed by condensation with hydroxylamine. © 2011 Published by Elsevier Ltd.

ANIMESH PRAMANIK

Chemistry

S DAS

P KOLEY

University of Calcutta (informally known as Calcutta University or CU) is a collegiate public state university located in Kolkata, West Bengal, India.&nbsp;Within India it is recognized as a &quot;Five-Star University&quot; and accredited &quot;A&quot; Grade by National Assessment and Accreditation Council.

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The University of Calcutta has secured the Fifth position among the Universities of India in the prestigious &quot;Indian University Ranking 2019&quot; list, released by the NIRF of the Ministry of Human Resource Development, Government of India.

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It was established on 24 January 1857, and was one of the first institutions in Asia to be established as a multidisciplinary and Western-style university. Its alumni and faculty include several heads of state, heads of government, social reformers, prominent artists, only academy award winner and Dirac medal winner in India, many Fellows of the Royal Society and five Nobel laureates as of 2019 which is highest in South Asia.

University Of Calcutta

Tetrahedron Letters

An efficient methodology for the synthesis of 3H,3′H- spiro[benzofuran-2,1′-isoindole]-3,3′-diones has been developed where monobromomalononitrile (MBM) has been employed as a non-hazardous brominating agent under ambient reaction condition. The intrinsic advantages of the methodology are the utilization of simple and easily available starting materials and non-toxic reagents, operational simplicity, and good yields of the products with high atom-economy.

Facile synthesis of 3H,3â€²H-spiro[benzofuran-2,1â€²-isoindole]-3, 3â€²-diones using monobromomalononitrile (MBM) as an efficient organo-brominating agent

A convenient and efficient methodology for the synthesis of densely substituted pyrrole-fused isocoumarins, which employs solidsupported silica sulfuric acid (SSA) as catalyst, has been developed. When the mixture of ninhydrin adducts of acetylacetone/ethyl acetoacetate and primary amines was heated on the solid surface of SSA under solvent-free conditions, the pyrrole-fused isocoumarins were formed in good yields. This synthetic method has several advantages such as the employment of solvent-free reaction conditions without the use of any toxic reagents and metal catalysts, the ease of product isolation, the use of a recyclable catalyst, the low cost, the easy availability of the starting materials, and the excellent yields of products. © 2013 Pathak et al.

Fulltext

Beilstein Journal of Organic Chemistry

Silica sulfuric acid: A reusable solid catalyst for one pot synthesis of densely substituted pyrrole-fused isocoumarins under solvent-free conditions

European Journal of Medicinal Chemistry

Synthesis and evaluation of benzoxazinone derivatives on activity of human neutrophil elastase and on hemorrhagic shock-induced lung injury in rats

Natural Product Reports

Rediscovering the bioactivity and ecological role of 1,4-benzoxazinones

Cold Spring Harbor Protocols

Cytochalasin B (5 mg/mL in DMSO)

Bioorganic & Medicinal Chemistry

Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors

Bioorganic & Medicinal Chemistry Letters

Synthesis and evaluation of analogs of Efavirenz (SUSTIVATM) as HIV-1 reverse transcriptase inhibitors

A simple synthesis of 4-substituted 2,3-benzoxazinones from C-2 arylated 1,3-indanediones

Journal	Data powered by TypesetTetrahedron Letters
Publisher	Data powered by TypesetPERGAMON-ELSEVIER SCIENCE LTD
ISSN	0040-4039
Open Access	No