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A response adaptive design for ordinal categorical responses
A BISWAS, , S DAS
Published in Taylor and Francis Inc.
2018
PMID: 29504826
Volume: 28
   
Issue: 6
Pages: 1169 - 1181
Abstract
A two treatment response adaptive design is developed for phase III clinical trials with ordinal categorical treatment outcome using Goodman-Kruskal measure of association. Properties of the proposed design are studied both empirically and theoretically and the acceptability is further illustrated using two real data-sets; one from a clinical trial with trauma patients and the other from a trial with patients having rheumatoid arthritis. © 2018, © 2018 Taylor & Francis.
About the journal
JournalData powered by TypesetJournal of Biopharmaceutical Statistics
PublisherData powered by TypesetTaylor and Francis Inc.
ISSN1054-3406
Open AccessNo