A novel thionation protocol for amide compounds, with the system rhodanine/secondary amine has been discovered. Clean and efficient synthesis of a variety of thioamides can be achieved through this simple and convenient method using MCM-41 mesoporous silica as an acid catalyst. For this purpose we have synthesized MCM-41 silica and characterized by using an array of sophisticated analytical techniques like BET, HR TEM, EDX, XRD, 29Si MAS NMR and FTIR. This reaction is therefore a very neat example of a functional group interconversion. © 2013 Elsevier Ltd. All rights reserved.

CHHANDA MUKHOPADHYAY

Chemistry

S RAY

A BHAUMIK

A DUTTA

R J BUTCHER

University of Calcutta (informally known as Calcutta University or CU) is a collegiate public state university located in Kolkata, West Bengal, India.&nbsp;Within India it is recognized as a &quot;Five-Star University&quot; and accredited &quot;A&quot; Grade by National Assessment and Accreditation Council.

&nbsp;

The University of Calcutta has secured the Fifth position among the Universities of India in the prestigious &quot;Indian University Ranking 2019&quot; list, released by the NIRF of the Ministry of Human Resource Development, Government of India.

&nbsp;

It was established on 24 January 1857, and was one of the first institutions in Asia to be established as a multidisciplinary and Western-style university. Its alumni and faculty include several heads of state, heads of government, social reformers, prominent artists, only academy award winner and Dirac medal winner in India, many Fellows of the Royal Society and five Nobel laureates as of 2019 which is highest in South Asia.

University Of Calcutta

Tetrahedron Letters

A new facile and efficient one-pot three component approach for the preparation of 2, 3, 4-trisubstituted quinolines by (MCM-41)-pyridine catalyzed reaction of easily available substituted isatins and dialkylacetylenedicarboxylates in alcohol has been developed. The (MCM-41)-pyridine nanopowder catalyst has been synthesized and the catalyst has been carefully characterized by various techniques including FT-IR, XRD, HRTEM, EDS, N2-adsorption analysis etc. The materials obtained exhibit high surface area and a narrow distribution of mesoporosity. The key features of this methodology are mild reaction conditions, operational simplicity and facile product separation, high to excellent yields, as well as simple catalyst recovery and reusability. The most exciting feature of this cascade reaction is its mechanism involving the unusual ring opening of an isatin moiety, then recyclisation, aromatization followed by esterification. The synthesized substituted quinolines are expected to be used as lead compounds for the development of new drugs. © 2019 Wiley-VCH Verlag GmbH &amp; Co. KGaA, Weinheim

ChemistrySelect

Mesoporous MCM-41 Silica Supported Pyridine Nanoparticle: A Highly Efficient, Recyclable Catalyst for Expeditious Synthesis of Quinoline Derivatives through Domino Approach

This is the first report of a sustainable and toxic metal free synthesis of benzothiazoles by the cleavage of ortho-aminothiophenol disulfide using a silica-supported heterogeneous catalyst in water in the presence of molecular O2 as a stoichiometric oxidant. For this purpose a new heterogeneous catalyst (MCM-PP) was synthesized by post synthesis grafting of 2-(piperazin-1-yl)pyrimidine functionalized organosilane onto MCM-41 mesoporous silica and it was characterized by BET surface area analysis, SAXRD, UHR TEM, CHN analysis, 13C CP MAS and 29Si MAS NMR. The reaction requires two different catalytic functions, i.e., an acidic one which is given by MCM-41 and a basic one, given by the organic base moiety anchored to the MCM-41. The greenness of the process was assured as water was exploited as the reaction medium and O2 from air as the stoichiometric oxidant. Furthermore the leaching of the active site can also be avoided as the organic moieties are covalently attached to the inorganic support. Standard leaching experiments proved that the reaction was heterogeneous with this recyclable catalyst. © The Royal Society of Chemistry.

RSC Advances

Piperazinylpyrimidine modified MCM-41 for the ecofriendly synthesis of benzothiazoles by the simple cleavage of disulfide in the presence of molecular O2

A chromatography free synthesis of 2-amino-5-isatinylidenethiazol-4-ones from rhodanine, isatin, and amine under environmentally benevolent conditions is reported for the first time. The molecular scaffolds assimilating both indolinone and thiazolidinone moieties are reported to have great biological significance. © 2013 Elsevier Ltd. All rights reserved.

Synthesis of molecular scaffolds assimilating both indolinone and thiazolidinone moieties under environmentally benevolent conditions

A new application of rhodanine as a green sulfur transferring agent for a clean functional group interconversion of amide to thioamide using reusable MCM-41 mesoporous silica

Journal	Data powered by TypesetTetrahedron Letters
Publisher	Data powered by TypesetPERGAMON-ELSEVIER SCIENCE LTD
ISSN	0040-4039
Open Access	No